Hope Karnes, MD, PhD, is a Board-certified pathologist and Medical Director at ExamOne, a Quest Diagnostics Company. Dr. Karnes completed her residency, chief residency, and fellowship at Washington University School of Medicine in St. Louis, Missouri. Prior to joining ExamOne, Dr. Karnes worked as a general pathologist in both the private and governmental sectors. From 2018-2022, Dr. Karnes worked as a Medical Advisor for Quest Diagnostics, supporting client engagement and education across the Esoteric Laboratories. In 2023, she joined Quest’s Medical Affairs division, where she led payer and reimbursement strategies for the myeloproliferative neoplasm portfolio within hematopathology. Most recently, Dr. Karnes has been providing medical support to Quest’s Diagnostic Services division, including ExamOne. She enjoys teaching and promoting appropriate laboratory test stewardship practices among clinical and laboratory colleagues and was named a “40 Under Forty” selectee for laboratory leadership by the American Society for Clinical Pathology (ASCP).